INHIBITION OF GAP JUNCTIONAL INTERCELLULAR COMMUNICATION IN WB-F344 RAT LIVER EPITHELIAL CELLS BY TRIPHENYLTIN CHLORIDE THROUGH MAPK AND PI3-KINASE PATHWAYS

Abstract Background Organotin compounds (OTCs) have been widely used as stabilizers in the production of plastic, agricultural pesticides, antifoulant plaints and wood preservation.The toxicity of triphenyltin (TPT) compounds was known for their embryotoxic, neurotoxic, genotoxic and immunotoxic effects in mammals.The carcinogenicity of TPT was not

ULUM is an new academic refereed journal dedicated to publishing articles, essays, translations, symposium reviews, and book reviews primarily within the fields of Religious and Islamic Studies including Arts and Humanities, Religion, Islamic Studies as well as Social and Behavioral Sciences, Theology and Ethics.The objective of the journal is to p

Coronavirus-like organisms have been previously identified in Arthropod ectoparasites (such as ticks and unfed cat flea).Yet, the question regarding the possible role of these arthropods as SARS-CoV-2 passive/biological transmission vectors is still poorly explored.In this study, we performed in silico structural and binding energy calculations to

Antimicrobial resistance happens when microorganisms mutates in manners that render the drugs like antibacterial, antiviral, antiparasitic and antifungal, ineffective.The normal mutation process is encouraged Solar Hybrid Invertor by the improper use of antibiotics.Mutations leading to quinolone resistance occur in a highly conserved region of the